| Children |
| | 1. George John Frederick WEST, Viscount Cantelupe, b. 26 Apr 1814 d. 25 Jun 1850 (Age 36 years) |
| | 2. Maj. Gen. Lord Charles Richard SACKVILLE-WEST, 6th Earl De La Warr, b. 13 Nov 1815, Upper Grosvenor, Westminster, Middlesex, England d. 23 Apr 1873 (Age 57 years) |
| | 3. Lord Reginald Windsor Sackville WEST, 7th Earl De La Warr, b. 21 Feb 1817, Upper Grosvenor, Westminster, Middlesex, England d. 5 Jan 1896, Upper Grosvenor, Westminster, Middlesex, England (Age 78 years) |
| > | 4. Lady Elizabeth SACKVILLE-WEST, b. 23 Sep 1818, England d. 22 Apr 1897, Chesham, Buckinghamshire, England (Age 78 years)
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| | 5. Mortimer SACKVILLE-WEST, 1st Baron Sackville, b. 22 Sep 1820 d. 1 Oct 1888 (Age 68 years) |
| | 6. WEST, b. 1822 d. 1823 (Age 1 year) |
| + | 7. Mary Catherine SACKVILLE-WEST, Coumtess of Derby, b. 1824 d. 6 Dec 1900, Holwood Park, Keston, Kent, England (Age 76 years)
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| | 8. Lionel SACKVILLE-WEST, 2nd Baron of Sackville, b. 19 Jul 1827, Bourn, Cambridgeshire, England d. 3 Sep 1908, Knole House, Sevenoaks, Kent, England (Age 81 years) |
| + | 9. Hon. William Edward SACKVILLE-WEST, b. 27 Oct 1830 d. 30 Sep 1905 (Age 74 years)
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| > | 10. Lady Arabella Diana SACKVILLE-WEST, b. 1835 d. 10 Feb 1869 (Age 34 years)
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