| # | Children | Name | Born | Died | Father | Mother |
|---|
| 1 | | | b. 27 Dec 1793 | d. 1 Jul 1857 | His Grace George SPENCER-CHURCHILL, 5th Duke of Marlborough, FSA | Susan STEWART, Duchess of Marlborough |
| 2 | | | b. 3 Dec 1794 | d. 28 Apr 1840 | His Grace George SPENCER-CHURCHILL, 5th Duke of Marlborough, FSA | Susan STEWART, Duchess of Marlborough |
| 3 | | | b. 1796 | d. 1828 | His Grace George SPENCER-CHURCHILL, 5th Duke of Marlborough, FSA | Susan STEWART, Duchess of Marlborough |
| 4 | | | b. 1797 | d. 2 Jun 1840 | His Grace George SPENCER-CHURCHILL, 5th Duke of Marlborough, FSA | Susan STEWART, Duchess of Marlborough |
| 5 | | | b. 1802 | d. 1880 | His Grace George SPENCER-CHURCHILL, 5th Duke of Marlborough, FSA | Unknown |
| 6 | | | b. 1819 | d. 1898 | His Grace George SPENCER-CHURCHILL, 5th Duke of Marlborough, FSA | Matilda GLOVER |
| 7 | | | b. 1823 | d. 1878 | His Grace George SPENCER-CHURCHILL, 5th Duke of Marlborough, FSA | Matilda GLOVER |
| 8 | | | b. 1825 | d. 1905 | His Grace George SPENCER-CHURCHILL, 5th Duke of Marlborough, FSA | Matilda GLOVER |
| 9 | | | b. 1831 | d. 1831 | His Grace George SPENCER-CHURCHILL, 5th Duke of Marlborough, FSA | Matilda GLOVER |
1766 - 1840 (73 years)